MLN 8237


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83 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 1
2 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 9
3 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 1
4 androgen receptor ANDR_HUMAN AR Homo sapiens 367 1832 1
5 annexin A5 ANXA5_HUMAN ANXA5 Homo sapiens 308 1785 1
6 aquaporin 2 AQP2_RAT Aqp2 Rattus norvegicus 25386 198 1
7 ATM serine/threonine kinase ATM_HUMAN ATM Homo sapiens 472 847 1
8 aurora kinase A AURKA_HUMAN AURKA Homo sapiens 6790 433 110
9 aurora kinase A AURKA_MOUSE Aurka Mus musculus 20878 82 15
10 aurora kinase B AURKB_HUMAN AURKB Homo sapiens 9212 244 1
11 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 1
12 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 2
13 B cell leukemia/lymphoma 2 BCL2_MOUSE Bcl2 Mus musculus 12043 1497 1
14 BH3 interacting domain death agonist BID_HUMAN BID Homo sapiens 637 1130 2
15 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 1
16 BRCA2 DNA repair associated BRCA2_HUMAN BRCA2 Homo sapiens 675 305 1
17 cadherin 1 CADH1_HUMAN CDH1 Homo sapiens 999 1360 1
18 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 2
19 CD34 molecule CD34_HUMAN CD34 Homo sapiens 947 1218 1
20 CD38 molecule CD38_HUMAN CD38 Homo sapiens 952 501 1
21 CD8a molecule CD8A_HUMAN CD8A Homo sapiens 925 1925 1
22 cell division cycle 20 CDC20_MOUSE Cdc20 Mus musculus 107995 16 1
23 cyclin dependent kinase 1 CDK1_HUMAN CDK1 Homo sapiens 983 1023 1
24 cyclin dependent kinase 4 CDK4_HUMAN CDK4 Homo sapiens 1019 868 1
25 checkpoint kinase 2 CHK2_HUMAN CHEK2 Homo sapiens 11200 417 1
26 cytochrome P450 family 2 subfamily C member 8 CP2C8_HUMAN CYP2C8 Homo sapiens 1558 590 1
27 cytochrome P450 family 2 subfamily C member 9 CP2C9_HUMAN CYP2C9 Homo sapiens 1559 1244 1
28 cytochrome P450 family 2 subfamily C member 19 CP2CJ_HUMAN CYP2C19 Homo sapiens 1557 1098 1
29 cytochrome P450 family 2 subfamily D member 6 CP2D6_HUMAN CYP2D6 Homo sapiens 1565 1531 1
30 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 3
31 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 1
32 DNA methyltransferase 1 DNMT1_HUMAN DNMT1 Homo sapiens 1786 621 1
33 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 1
34 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 1
35 estrogen receptor 1 ESR1_HUMAN ESR1 Homo sapiens 2099 3003 1
36 enhancer of zeste 2 polycomb repressive complex 2 subunit EZH2_HUMAN EZH2 Homo sapiens 2146 470 2
37 forkhead box O3 FOXO3_HUMAN FOXO3 Homo sapiens 2309 544 1
38 GLI family zinc finger 2 GLI2_HUMAN GLI2 Homo sapiens 2736 1670 1
39 glycogen synthase kinase 3 beta GSK3B_HUMAN GSK3B Homo sapiens 2932 1189 1
40 histone H3 associated protein kinase HASP_MOUSE Haspin Mus musculus 14841 11 1
41 histone deacetylase 6 HDAC6_HUMAN HDAC6 Homo sapiens 10013 454 1
42 eukaryotic translation initiation factor 4E IF4E_MOUSE Eif4e Mus musculus 13684 78 1
43 interferon alpha inducible protein 27 IFI27_HUMAN IFI27 Homo sapiens 3429 662 1
44 Janus kinase 2 JAK2_HUMAN JAK2 Homo sapiens 3717 1038 1
45 lysine demethylase 1A KDM1A_HUMAN KDM1A Homo sapiens 23028 403 1
46 lysine demethylase 6B KDM6B_HUMAN KDM6B Homo sapiens 23135 93 1
47 ribosomal protein S6 kinase B1 KS6B1_HUMAN RPS6KB1 Homo sapiens 6198 764 1
48 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 1
49 MDM2 proto-oncogene MDM2_HUMAN MDM2 Homo sapiens 4193 873 1
50 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 3